Haruaki Nobori Selected Research

ensitrelvir

2/2024	Prophylactic effect of ensitrelvir in mice infected with SARS-CoV-2.
12/2023	Combination therapy with oral antiviral and anti-inflammatory drugs improves the efficacy of delayed treatment in a COVID-19 hamster model.
10/2023	Pharmacokinetic and Pharmacodynamic Analysis of the 3CL Protease Inhibitor Ensitrelvir in a SARS-CoV-2 Infection Mouse Model.
1/2023	S-217622, a SARS-CoV-2 main protease inhibitor, decreases viral load and ameliorates COVID-19 severity in hamsters.
1/2023	Ensitrelvir is effective against SARS-CoV-2 3CL protease mutants circulating globally.
12/2022	Discovery of S-217622, a Noncovalent Oral SARS-CoV-2 3CL Protease Inhibitor Clinical Candidate for Treating COVID-19.
10/2022	Efficacy of ensitrelvir against SARS-CoV-2 in a delayed-treatment mouse model.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Haruaki Nobori Research Topics

Disease

10	Infections 02/2024 - 04/2016
8	COVID-19 02/2024 - 10/2021
3	Pneumonia (Pneumonitis) 12/2023 - 01/2022
2	Body Weight (Weight, Body) 02/2024 - 10/2022
2	Influenza in Birds (Avian Flu) 01/2022 - 01/2019
2	Virus Diseases (Viral Diseases) 01/2022 - 04/2016
1	Body Weight Changes 02/2024
1	Human Influenza (Influenza) 01/2019
1	Rabies (Hydrophobia) 04/2016

Drug/Important Bio-Agent (IBA)

7	ensitrelvirIBA 02/2024 - 10/2022
7	Antiviral Agents (Antivirals)IBA 12/2023 - 04/2016
2	Protease Inhibitors (Protease Inhibitor)IBA 10/2023 - 12/2022
2	baloxavirIBA 01/2022 - 01/2019
1	Immunologic Factors (Immunomodulators)IBA 12/2023
1	Adrenal Cortex Hormones (Corticosteroids)IBA 12/2023
1	Methylprednisolone FDA LinkGeneric 12/2023
1	Peptide Hydrolases (Proteases)FDA Link 01/2023
1	SARS-CoV-2 3C-like proteinaseIBA 01/2023
1	ChemokinesIBA 10/2022
1	Nucleocapsid ProteinsIBA 10/2022
1	CytokinesIBA 10/2022
1	Oseltamivir (Tamiflu)FDA Link 01/2022
1	Phosphates (Orthophosphate)IBA 01/2022
1	Viral RNAIBA 10/2021
1	MethyltransferasesIBA 12/2020
1	EndonucleasesIBA 01/2019
1	favipiravirIBA 01/2019
1	Therapeutic UsesIBA 01/2019
1	benzimidazoleIBA 01/2017
1	nanolucIBA 04/2016
1	LuciferasesIBA 04/2016

Therapy/Procedure

2	Therapeutics 12/2023 - 04/2016
1	Treatment Delay 12/2023
1	Oral Administration 01/2023